Activation of the aryl hydrocarbon receptor pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer. [electronic resource]
Producer: 20100304Description: 287-95 p. digitalISSN:- 1460-2180
- Adult
- Aged
- Aged, 80 and over
- Apoptosis
- Aryl Hydrocarbon Hydroxylases
- Blotting, Western
- Carcinoma, Transitional Cell -- metabolism
- Cell Adhesion
- Cell Line, Tumor
- Cell Movement
- Cell Proliferation
- Cytochrome P-450 CYP1A1 -- genetics
- Cytochrome P-450 CYP1B1
- Cytochrome P-450 Enzyme System -- genetics
- Female
- Humans
- Immunoenzyme Techniques
- Kidney Neoplasms -- metabolism
- Male
- Matrix Metalloproteinase 1 -- metabolism
- Matrix Metalloproteinase 9 -- metabolism
- Middle Aged
- Neoplasm Invasiveness
- Polychlorinated Dibenzodioxins -- pharmacology
- Prognosis
- RNA, Messenger -- genetics
- RNA, Small Interfering -- pharmacology
- Receptors, Aryl Hydrocarbon -- antagonists & inhibitors
- Reverse Transcriptase Polymerase Chain Reaction
- Survival Rate
- Ureteral Neoplasms -- metabolism
- Urothelium -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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