Activation of the aryl hydrocarbon receptor pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer.

Ishida, Masaru

Activation of the aryl hydrocarbon receptor pathway enhances cancer cell invasion by upregulating the MMP expression and is associated with poor prognosis in upper urinary tract urothelial cancer. [electronic resource] - Carcinogenesis Feb 2010 - 287-95 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2180

10.1093/carcin/bgp222 doi


Adult
Aged
Aged, 80 and over
Apoptosis
Aryl Hydrocarbon Hydroxylases
Blotting, Western
Carcinoma, Transitional Cell--metabolism
Cell Adhesion
Cell Line, Tumor
Cell Movement
Cell Proliferation
Cytochrome P-450 CYP1A1--genetics
Cytochrome P-450 CYP1B1
Cytochrome P-450 Enzyme System--genetics
Female
Humans
Immunoenzyme Techniques
Kidney Neoplasms--metabolism
Male
Matrix Metalloproteinase 1--metabolism
Matrix Metalloproteinase 9--metabolism
Middle Aged
Neoplasm Invasiveness
Polychlorinated Dibenzodioxins--pharmacology
Prognosis
RNA, Messenger--genetics
RNA, Small Interfering--pharmacology
Receptors, Aryl Hydrocarbon--antagonists & inhibitors
Reverse Transcriptase Polymerase Chain Reaction
Survival Rate
Ureteral Neoplasms--metabolism
Urothelium--metabolism