Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). [electronic resource]
Producer: 20091113Description: 778-88 p. digitalISSN:- 1097-4652
- Adolescent
- Animals
- Antigens, CD -- metabolism
- Asian People
- Calcification, Physiologic -- physiology
- Cell Cycle -- drug effects
- Cell Dedifferentiation
- Cell Differentiation
- Cell Line, Tumor
- Cell Proliferation
- Child
- Chromosome Aberrations
- Collagen Type I -- metabolism
- Core Binding Factor Alpha 1 Subunit -- genetics
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Cyclins -- genetics
- Female
- Gene Expression -- genetics
- Humans
- Ki-67 Antigen -- metabolism
- Mice
- Mice, SCID
- Nocodazole -- pharmacology
- Osteoblasts -- pathology
- Osteocalcin -- metabolism
- Osteosarcoma -- diagnosis
- Retinoblastoma Protein -- genetics
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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