Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

Pereira, Barry P

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). [electronic resource] - Journal of cellular physiology Dec 2009 - 778-88 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1097-4652

10.1002/jcp.21921 doi


Adolescent
Animals
Antigens, CD--metabolism
Asian People
Calcification, Physiologic--physiology
Cell Cycle--drug effects
Cell Dedifferentiation
Cell Differentiation
Cell Line, Tumor
Cell Proliferation
Child
Chromosome Aberrations
Collagen Type I--metabolism
Core Binding Factor Alpha 1 Subunit--genetics
Cyclin-Dependent Kinase Inhibitor p21--metabolism
Cyclins--genetics
Female
Gene Expression--genetics
Humans
Ki-67 Antigen--metabolism
Mice
Mice, SCID
Nocodazole--pharmacology
Osteoblasts--pathology
Osteocalcin--metabolism
Osteosarcoma--diagnosis
Retinoblastoma Protein--genetics
Tumor Suppressor Protein p53--genetics
Xenograft Model Antitumor Assays