A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo. [electronic resource]
Producer: 20091113Description: 5729-41 p. digitalISSN:- 1098-5549
- Animals
- Cardiomegaly -- complications
- Cardiomyopathies -- complications
- Cell Hypoxia
- Enzyme Activation
- Feedback, Physiological
- Heart Function Tests
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Hypoxia-Inducible Factor-Proline Dioxygenases
- Kidney -- enzymology
- Liver -- enzymology
- Mammals -- metabolism
- Mice
- Mitochondria -- enzymology
- Myocardium -- enzymology
- Polycythemia -- complications
- Procollagen-Proline Dioxygenase -- deficiency
- Survival Analysis
- Von Hippel-Lindau Tumor Suppressor Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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