Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha. [electronic resource]
Producer: 20091021Description: 27042-53 p. digitalISSN:- 1083-351X
- Acetylation -- drug effects
- Animals
- Base Sequence
- Binding Sites
- Cell Line
- Cytosol -- enzymology
- DNA -- metabolism
- Enzyme Activation -- drug effects
- Gene Expression Regulation, Enzymologic -- drug effects
- Hepatocyte Nuclear Factor 4 -- metabolism
- Humans
- Molecular Sequence Data
- Niacinamide -- pharmacology
- Phosphoenolpyruvate Carboxykinase (GTP) -- chemistry
- Promoter Regions, Genetic -- genetics
- Resveratrol
- Sirtuins -- metabolism
- Stilbenes -- pharmacology
- Transcription Factor AP-1 -- metabolism
- Transcription, Genetic -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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