Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha.
Yang, Jianqi
Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha. [electronic resource] - The Journal of biological chemistry Oct 2009 - 27042-53 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1083-351X
10.1074/jbc.M109.047340 doi
Acetylation--drug effects
Animals
Base Sequence
Binding Sites
Cell Line
Cytosol--enzymology
DNA--metabolism
Enzyme Activation--drug effects
Gene Expression Regulation, Enzymologic--drug effects
Hepatocyte Nuclear Factor 4--metabolism
Humans
Molecular Sequence Data
Niacinamide--pharmacology
Phosphoenolpyruvate Carboxykinase (GTP)--chemistry
Promoter Regions, Genetic--genetics
Resveratrol
Sirtuins--metabolism
Stilbenes--pharmacology
Transcription Factor AP-1--metabolism
Transcription, Genetic--drug effects
Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha. [electronic resource] - The Journal of biological chemistry Oct 2009 - 27042-53 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1083-351X
10.1074/jbc.M109.047340 doi
Acetylation--drug effects
Animals
Base Sequence
Binding Sites
Cell Line
Cytosol--enzymology
DNA--metabolism
Enzyme Activation--drug effects
Gene Expression Regulation, Enzymologic--drug effects
Hepatocyte Nuclear Factor 4--metabolism
Humans
Molecular Sequence Data
Niacinamide--pharmacology
Phosphoenolpyruvate Carboxykinase (GTP)--chemistry
Promoter Regions, Genetic--genetics
Resveratrol
Sirtuins--metabolism
Stilbenes--pharmacology
Transcription Factor AP-1--metabolism
Transcription, Genetic--drug effects