Sustained inhibition of tumor growth and prolonged survival following sequential administration of doxorubicin and zoledronic acid in a breast cancer model. [electronic resource]
Producer: 20100113Description: 522-32 p. digitalISSN:- 1097-0215
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins -- genetics
- Blotting, Western
- Breast Neoplasms -- drug therapy
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Diphosphonates -- administration & dosage
- Doxorubicin -- administration & dosage
- Drug Administration Schedule
- Female
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Humans
- Imidazoles -- administration & dosage
- Kaplan-Meier Estimate
- Mammary Neoplasms, Experimental -- drug therapy
- Mice
- Mice, Nude
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Burden
- Xenograft Model Antitumor Assays
- Zoledronic Acid
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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