Sustained inhibition of tumor growth and prolonged survival following sequential administration of doxorubicin and zoledronic acid in a breast cancer model.

Ottewell, Penelope D

Sustained inhibition of tumor growth and prolonged survival following sequential administration of doxorubicin and zoledronic acid in a breast cancer model. [electronic resource] - International journal of cancer Jan 2010 - 522-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-0215

10.1002/ijc.24756 doi


Animals
Antineoplastic Combined Chemotherapy Protocols--therapeutic use
Apoptosis--drug effects
Apoptosis Regulatory Proteins--genetics
Blotting, Western
Breast Neoplasms--drug therapy
Cell Cycle--drug effects
Cell Cycle Proteins--genetics
Cell Line, Tumor
Diphosphonates--administration & dosage
Doxorubicin--administration & dosage
Drug Administration Schedule
Female
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Humans
Imidazoles--administration & dosage
Kaplan-Meier Estimate
Mammary Neoplasms, Experimental--drug therapy
Mice
Mice, Nude
Reverse Transcriptase Polymerase Chain Reaction
Tumor Burden
Xenograft Model Antitumor Assays
Zoledronic Acid