Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: an endpoint/toxic response where data from multiple chemicals converge to support a mode of action. [electronic resource]
Producer: 20091211Description: 205-18 p. digitalISSN:- 1096-0295
- Adenocarcinoma -- chemically induced
- Adenoma -- chemically induced
- Animals
- Bronchioles -- drug effects
- Carcinogens -- chemistry
- Cell Proliferation -- drug effects
- Coumarins -- chemistry
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- metabolism
- Disease Models, Animal
- Endpoint Determination
- Enzyme Inhibitors -- pharmacology
- Epithelial Cells -- drug effects
- Humans
- Inhalation Exposure
- Isoenzymes
- Lung Neoplasms -- chemically induced
- Mice
- Mice, Knockout
- Mutagenicity Tests
- Naphthalenes -- chemistry
- Rats
- Structure-Activity Relationship
- Styrene -- chemistry
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Publication Type: Journal Article; Review
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