Preclinical evaluation of an anti-CD25 monoclonal antibody, 7G7/B6, armed with the beta-emitter, yttrium-90, as a radioimmunotherapeutic agent for treating lymphoma. [electronic resource]
Producer: 20090928Description: 303-9 p. digitalISSN:- 1557-8852
- Animals
- Antibodies, Monoclonal -- immunology
- Antibodies, Monoclonal, Humanized
- Antibody Specificity -- immunology
- Cell Line, Tumor
- Daclizumab
- Disease-Free Survival
- Endocytosis -- immunology
- Female
- Humans
- Immunoglobulin G -- metabolism
- Immunosuppressive Agents -- metabolism
- Interleukin-2 Receptor alpha Subunit -- immunology
- Kaplan-Meier Estimate
- Lymphoma -- pathology
- Maximum Tolerated Dose
- Mice
- Mice, Nude
- Radioimmunotherapy -- methods
- Xenograft Model Antitumor Assays
- Yttrium Radioisotopes -- therapeutic use
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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