Preclinical evaluation of an anti-CD25 monoclonal antibody, 7G7/B6, armed with the beta-emitter, yttrium-90, as a radioimmunotherapeutic agent for treating lymphoma.

Zhang, Meili

Preclinical evaluation of an anti-CD25 monoclonal antibody, 7G7/B6, armed with the beta-emitter, yttrium-90, as a radioimmunotherapeutic agent for treating lymphoma. [electronic resource] - Cancer biotherapy & radiopharmaceuticals Jun 2009 - 303-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

1557-8852

10.1089/cbr.2008.0577 doi


Animals
Antibodies, Monoclonal--immunology
Antibodies, Monoclonal, Humanized
Antibody Specificity--immunology
Cell Line, Tumor
Daclizumab
Disease-Free Survival
Endocytosis--immunology
Female
Humans
Immunoglobulin G--metabolism
Immunosuppressive Agents--metabolism
Interleukin-2 Receptor alpha Subunit--immunology
Kaplan-Meier Estimate
Lymphoma--pathology
Maximum Tolerated Dose
Mice
Mice, Nude
Radioimmunotherapy--methods
Xenograft Model Antitumor Assays
Yttrium Radioisotopes--therapeutic use