The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel. [electronic resource]
Producer: 20091019Description: 2027-35 p. digitalISSN:- 1538-8514
- Actins -- metabolism
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Proliferation
- Drug Therapy, Combination
- Female
- Fluorescent Antibody Technique
- Focal Adhesions -- metabolism
- Humans
- Mice
- Mice, Nude
- Neoplasm Invasiveness
- Oligonucleotides
- Oligopeptides -- pharmacology
- Paclitaxel -- pharmacology
- Telomerase -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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