The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel.
Goldblatt, Erin M
The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel. [electronic resource] - Molecular cancer therapeutics Jul 2009 - 2027-35 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-8514
10.1158/1535-7163.MCT-08-1188 doi
Actins--metabolism
Animals
Antineoplastic Agents, Phytogenic--pharmacology
Breast Neoplasms--drug therapy
Cell Line, Tumor
Cell Proliferation
Drug Therapy, Combination
Female
Fluorescent Antibody Technique
Focal Adhesions--metabolism
Humans
Mice
Mice, Nude
Neoplasm Invasiveness
Oligonucleotides
Oligopeptides--pharmacology
Paclitaxel--pharmacology
Telomerase--antagonists & inhibitors
Xenograft Model Antitumor Assays
The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel. [electronic resource] - Molecular cancer therapeutics Jul 2009 - 2027-35 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-8514
10.1158/1535-7163.MCT-08-1188 doi
Actins--metabolism
Animals
Antineoplastic Agents, Phytogenic--pharmacology
Breast Neoplasms--drug therapy
Cell Line, Tumor
Cell Proliferation
Drug Therapy, Combination
Female
Fluorescent Antibody Technique
Focal Adhesions--metabolism
Humans
Mice
Mice, Nude
Neoplasm Invasiveness
Oligonucleotides
Oligopeptides--pharmacology
Paclitaxel--pharmacology
Telomerase--antagonists & inhibitors
Xenograft Model Antitumor Assays