Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1. [electronic resource]
Producer: 20090909Description: 171-80 p. digitalISSN:- 1470-8728
- Amino Acid Sequence
- Amino Acid Substitution
- Antioxidants -- metabolism
- Biocatalysis
- Cell Line, Tumor
- Conserved Sequence
- Cullin Proteins -- metabolism
- Cysteine -- genetics
- Humans
- Intracellular Signaling Peptides and Proteins -- chemistry
- Kelch-Like ECH-Associated Protein 1
- Models, Molecular
- Molecular Sequence Data
- Mutant Proteins -- chemistry
- NF-E2-Related Factor 2 -- metabolism
- Protein Binding
- Protein Stability
- Response Elements -- genetics
- Structure-Activity Relationship
- Tryptophan -- genetics
- Ubiquitination
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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