Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.

Eggler, Aimee L

Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1. [electronic resource] - The Biochemical journal Jul 2009 - 171-80 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1470-8728

10.1042/BJ20090471 doi


Amino Acid Sequence
Amino Acid Substitution
Antioxidants--metabolism
Biocatalysis
Cell Line, Tumor
Conserved Sequence
Cullin Proteins--metabolism
Cysteine--genetics
Humans
Intracellular Signaling Peptides and Proteins--chemistry
Kelch-Like ECH-Associated Protein 1
Models, Molecular
Molecular Sequence Data
Mutant Proteins--chemistry
NF-E2-Related Factor 2--metabolism
Protein Binding
Protein Stability
Response Elements--genetics
Structure-Activity Relationship
Tryptophan--genetics
Ubiquitination