Chemical genetic profiling and characterization of small-molecule compounds that affect the biosynthesis of unsaturated fatty acids in Candida albicans. [electronic resource]
Producer: 20090925Description: 19754-64 p. digitalISSN:- 0021-9258
- Animals
- Antifungal Agents -- chemistry
- Candida albicans -- genetics
- Candidiasis -- microbiology
- Cerulenin -- pharmacology
- Cluster Analysis
- Fatty Acid Desaturases -- genetics
- Fatty Acids, Unsaturated -- biosynthesis
- Fungal Proteins -- genetics
- Gene Expression Profiling
- Gene Expression Regulation, Fungal -- drug effects
- Hyphae -- drug effects
- Male
- Mice
- Mice, Inbred ICR
- Molecular Structure
- Mutation
- Stearoyl-CoA Desaturase
- Survival Rate
- Thiazoles -- chemistry
- Time Factors
- Triazoles -- chemistry
- Virulence -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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