Chemical genetic profiling and characterization of small-molecule compounds that affect the biosynthesis of unsaturated fatty acids in Candida albicans.

Xu, Deming

Chemical genetic profiling and characterization of small-molecule compounds that affect the biosynthesis of unsaturated fatty acids in Candida albicans. [electronic resource] - The Journal of biological chemistry Jul 2009 - 19754-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M109.019877 doi


Animals
Antifungal Agents--chemistry
Candida albicans--genetics
Candidiasis--microbiology
Cerulenin--pharmacology
Cluster Analysis
Fatty Acid Desaturases--genetics
Fatty Acids, Unsaturated--biosynthesis
Fungal Proteins--genetics
Gene Expression Profiling
Gene Expression Regulation, Fungal--drug effects
Hyphae--drug effects
Male
Mice
Mice, Inbred ICR
Molecular Structure
Mutation
Stearoyl-CoA Desaturase
Survival Rate
Thiazoles--chemistry
Time Factors
Triazoles--chemistry
Virulence--genetics