Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites. [electronic resource]
Producer: 20090918Description: 897-906 p. digitalISSN:- 1557-3125
- Animals
- Antimetabolites, Antineoplastic -- pharmacology
- Antineoplastic Agents, Alkylating -- pharmacology
- Apoptosis -- drug effects
- CHO Cells
- Cell Cycle -- drug effects
- Cell Survival -- drug effects
- Cricetinae
- Cricetulus
- DNA Repair
- DNA-(Apurinic or Apyrimidinic Site) Lyase -- biosynthesis
- Fluorouracil -- pharmacology
- G1 Phase -- drug effects
- Humans
- Mutation
- Neoplasms -- drug therapy
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
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