PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models. [electronic resource]
Producer: 20090717Description: 1779-90 p. digitalISSN:- 1471-4159
- Analysis of Variance
- Animals
- Annexin A5 -- metabolism
- Antineoplastic Agents -- therapeutic use
- Brain Neoplasms -- drug therapy
- Bromodeoxyuridine -- metabolism
- Caspase 3 -- metabolism
- Cell Line, Tumor
- Cell Proliferation
- Cytochromes c -- metabolism
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Synergism
- Gene Expression Regulation, Neoplastic -- drug effects
- Glioma -- drug therapy
- Humans
- Ligands
- Matrix Metalloproteinases -- metabolism
- Mice
- Mice, Inbred C57BL
- Neoplasm Invasiveness -- physiopathology
- PPAR gamma -- metabolism
- Pioglitazone
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Rats
- Retinoid X Receptor gamma -- metabolism
- Tetrazolium Salts
- Thiazoles
- Thiazolidinediones -- therapeutic use
- Transfection -- methods
- Tretinoin -- analogs & derivatives
- Tumor Stem Cell Assay -- methods
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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