An orally bioavailable synthetic analog of an active dehydroepiandrosterone metabolite reduces established disease in rodent models of rheumatoid arthritis. [electronic resource]
Producer: 20090623Description: 1100-9 p. digitalISSN:- 1521-0103
- Animals
- Anti-Inflammatory Agents -- administration & dosage
- Antibodies -- immunology
- Antibody Formation -- drug effects
- Arthritis, Rheumatoid -- chemically induced
- Collagen -- immunology
- Cytokines -- genetics
- Dehydroepiandrosterone -- administration & dosage
- Disease Models, Animal
- Gene Expression -- drug effects
- Hypersensitivity, Delayed -- immunology
- Immune System -- drug effects
- Interleukin-6 -- genetics
- Joints -- drug effects
- Lipopolysaccharides -- pharmacology
- Lymph Nodes -- drug effects
- Male
- Matrix Metalloproteinase 3 -- genetics
- Mice
- Mice, Inbred DBA
- Mice, Inbred ICR
- NF-kappa B -- metabolism
- Spleen -- drug effects
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Publication Type: Journal Article
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