The ataxia3 mutation in the N-terminal cytoplasmic domain of sodium channel Na(v)1.6 disrupts intracellular trafficking. [electronic resource]
Producer: 20090410Description: 2733-41 p. digitalISSN:- 1529-2401
- Animals
- Blotting, Western
- Cell Line
- Chromosome Mapping
- Cytoplasm -- metabolism
- DNA, Complementary -- biosynthesis
- Data Interpretation, Statistical
- Electrophysiology
- Ethylnitrosourea
- Immunohistochemistry
- Machado-Joseph Disease -- genetics
- Mice
- Mice, Inbred C57BL
- Mutagens
- Mutation -- genetics
- Mutation, Missense -- genetics
- NAV1.6 Voltage-Gated Sodium Channel
- Nerve Tissue Proteins -- genetics
- Patch-Clamp Techniques
- Sciatic Nerve -- pathology
- Sodium Channels -- genetics
- Subcellular Fractions -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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