Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice. [electronic resource]
Producer: 20090714Description: 1633-41 p. digitalISSN:- 1460-2083
- Animals
- Base Sequence
- Disease Models, Animal
- Electrophysiology
- Epilepsy, Absence -- genetics
- Heterozygote
- Humans
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Transgenic
- Molecular Sequence Data
- Mutation
- Mutation, Missense
- NAV1.6 Voltage-Gated Sodium Channel
- Nerve Tissue Proteins -- genetics
- Phenotype
- Sodium Channels -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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