Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice.

Papale, Ligia A

Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice. [electronic resource] - Human molecular genetics May 2009 - 1633-41 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1460-2083

10.1093/hmg/ddp081 doi


Animals
Base Sequence
Disease Models, Animal
Electrophysiology
Epilepsy, Absence--genetics
Heterozygote
Humans
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Transgenic
Molecular Sequence Data
Mutation
Mutation, Missense
NAV1.6 Voltage-Gated Sodium Channel
Nerve Tissue Proteins--genetics
Phenotype
Sodium Channels--genetics