Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver. [electronic resource]
Producer: 20091208Description: 219-28 p. digitalISSN:- 1873-4596
- 6-Aminonicotinamide -- pharmacology
- Animals
- Cell Extracts
- Cells, Cultured
- Dehydroepiandrosterone -- pharmacology
- Diabetes Mellitus, Type 2 -- enzymology
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation, Enzymologic -- drug effects
- Gluconates -- pharmacology
- Glucosephosphate Dehydrogenase -- genetics
- Glycoproteins -- pharmacology
- Liver -- drug effects
- Male
- NADPH Oxidases -- genetics
- Obesity
- Pentose Phosphate Pathway -- drug effects
- Perfusion
- Phosphatidylinositol 3-Kinases -- metabolism
- Rats
- Rats, Zucker
- Signal Transduction
- Superoxides -- metabolism
- Up-Regulation -- drug effects
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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