Cellular growth inhibition by FK778 is linked to G1 arrest or S phase accumulation, dependent on the functional status of the retinoblastoma protein. [electronic resource]
Producer: 20090414Description: 415-20 p. digitalISSN:- 1107-3756
- Alkynes -- pharmacology
- Antiviral Agents -- pharmacology
- DNA-Binding Proteins -- biosynthesis
- G1 Phase -- drug effects
- HeLa Cells
- Human papillomavirus 16 -- metabolism
- Human papillomavirus 18 -- metabolism
- Humans
- Isoxazoles -- pharmacology
- Nitriles -- pharmacology
- Oncogene Proteins, Viral -- biosynthesis
- Papillomavirus E7 Proteins
- Phosphorylation -- drug effects
- Retinoblastoma Protein -- metabolism
- S Phase -- drug effects
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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