Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration. [electronic resource]
Producer: 20090521Description: e1000333 p. digitalISSN:- 1553-7404
- Animals
- Animals, Genetically Modified
- Cell Movement
- Dimethylallyltranstransferase -- genetics
- Drosophila -- cytology
- Drosophila Proteins -- genetics
- Farnesyltranstransferase -- genetics
- Female
- GTP-Binding Protein gamma Subunits -- genetics
- Germ Cells -- physiology
- Hedgehog Proteins -- genetics
- Hydroxymethylglutaryl CoA Reductases -- genetics
- Male
- Metabolic Networks and Pathways -- genetics
- Mevalonic Acid -- metabolism
- Mutation
- Protein Processing, Post-Translational -- genetics
- Receptors, G-Protein-Coupled -- genetics
- Smoothened Receptor
- Terpenes -- metabolism
- Wings, Animal -- anatomy & histology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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