The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity. [electronic resource]
Producer: 20090115Description: 952-63 p. digitalISSN:- 1471-4159
- Acetylcholine -- pharmacology
- Animals
- Behavior, Animal -- drug effects
- Bivalvia -- chemistry
- Bungarotoxins -- metabolism
- Cells, Cultured
- Chromatography, High Pressure Liquid -- methods
- Dose-Response Relationship, Drug
- Drug Interactions
- Electric Stimulation -- methods
- Gene Expression -- drug effects
- Heterocyclic Compounds, 3-Ring -- analysis
- Humans
- Hydrocarbons, Cyclic -- analysis
- Imines -- analysis
- Male
- Membrane Potentials -- drug effects
- Mice
- Mice, Inbred C57BL
- Muscle Cells -- drug effects
- Neuromuscular Junction -- drug effects
- Oocytes
- Patch-Clamp Techniques
- Protein Binding -- drug effects
- Receptors, Nicotinic -- metabolism
- Synaptic Transmission -- drug effects
- Xenopus laevis
- alpha7 Nicotinic Acetylcholine Receptor
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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