Detection of human survival motor neuron (SMN) protein in mice containing the SMN2 transgene: applicability to preclinical therapy development for spinal muscular atrophy. [electronic resource]
Producer: 20090409Description: 36-43 p. digitalISSN:- 0165-0270
- Alternative Splicing -- genetics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal -- metabolism
- Cells, Cultured
- Disease Models, Animal
- Enzyme Inhibitors
- Epitope Mapping -- methods
- Fibroblasts -- drug effects
- Gene Expression Regulation -- drug effects
- Humans
- Hydroxyurea -- therapeutic use
- Indoles
- Mice
- Mice, Transgenic -- metabolism
- Muscular Atrophy, Spinal -- drug therapy
- SMN Complex Proteins -- genetics
- Spinal Cord -- drug effects
- Survival of Motor Neuron 2 Protein
- Valproic Acid -- therapeutic use
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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