A RAG1 mutation found in Omenn syndrome causes coding flank hypersensitivity: a novel mechanism for antigen receptor repertoire restriction. [electronic resource]
Producer: 20081118Description: 4124-30 p. digitalISSN:- 1550-6606
- Amino Acid Motifs -- genetics
- Amino Acid Substitution -- genetics
- Animals
- Arginine -- genetics
- CHO Cells
- Catalytic Domain -- genetics
- Cricetinae
- Cricetulus
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Genes, T-Cell Receptor beta -- genetics
- Glutamine -- genetics
- Homeodomain Proteins -- genetics
- Humans
- Mice
- Mutagenesis, Site-Directed
- Severe Combined Immunodeficiency -- enzymology
- VDJ Recombinases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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