Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events. [electronic resource]
Producer: 20080916Description: 2172-7 p. digitalISSN:- 0890-9369
- Animals
- Blotting, Western
- Cell Line, Tumor
- Cell Transformation, Neoplastic -- pathology
- Chromosome Aberrations
- Humans
- Male
- Mechanistic Target of Rapamycin Complex 1
- Mice
- Mice, Transgenic
- Monomeric GTP-Binding Proteins -- physiology
- Multiprotein Complexes
- Neuropeptides -- physiology
- PTEN Phosphohydrolase -- physiology
- Prostatic Intraepithelial Neoplasia -- etiology
- Prostatic Neoplasms -- etiology
- Proteins
- Proto-Oncogene Mas
- RNA, Messenger -- genetics
- Ras Homolog Enriched in Brain Protein
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- TOR Serine-Threonine Kinases
- Transcription Factors -- physiology
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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