A strategy for systemic delivery of the oncolytic herpes virus HSV1716: redirected tropism by antibody-binding sites incorporated on the virion surface as a glycoprotein D fusion protein. [electronic resource]
Producer: 20090220Description: 1579-92 p. digitalISSN:- 1476-5462
- ADP-ribosyl Cyclase 1 -- immunology
- Animals
- Binding Sites, Antibody -- genetics
- CD55 Antigens -- immunology
- CHO Cells
- Cricetinae
- Cricetulus
- ErbB Receptors -- immunology
- Fluorescent Antibody Technique
- Genetic Therapy -- methods
- Glycoproteins -- genetics
- Humans
- Immunoglobulin Variable Region -- genetics
- Injections, Intraperitoneal
- Mice
- Mice, Nude
- Microscopy, Fluorescence
- Neoplasms -- immunology
- Oncolytic Virotherapy -- methods
- Oncolytic Viruses -- genetics
- Recombinant Fusion Proteins -- administration & dosage
- Simplexvirus -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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