Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins. [electronic resource]
Producer: 20081118Description: 6646-56 p. digitalISSN:- 1476-5594
- Animals
- Apoptosis -- drug effects
- Biphenyl Compounds -- pharmacology
- Cell Line, Tumor
- Glioblastoma -- genetics
- Humans
- Mice
- Neoplastic Stem Cells -- cytology
- Nitrophenols -- pharmacology
- Piperazines -- pharmacology
- Protein Binding
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- Sulfonamides -- pharmacology
- Survival Rate
- TNF-Related Apoptosis-Inducing Ligand -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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