Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins.
Tagscherer, K E
Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins. [electronic resource] - Oncogene Nov 2008 - 6646-56 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5594
10.1038/onc.2008.259 doi
Animals
Apoptosis--drug effects
Biphenyl Compounds--pharmacology
Cell Line, Tumor
Glioblastoma--genetics
Humans
Mice
Neoplastic Stem Cells--cytology
Nitrophenols--pharmacology
Piperazines--pharmacology
Protein Binding
Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors
Sulfonamides--pharmacology
Survival Rate
TNF-Related Apoptosis-Inducing Ligand--metabolism
Xenograft Model Antitumor Assays
Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins. [electronic resource] - Oncogene Nov 2008 - 6646-56 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5594
10.1038/onc.2008.259 doi
Animals
Apoptosis--drug effects
Biphenyl Compounds--pharmacology
Cell Line, Tumor
Glioblastoma--genetics
Humans
Mice
Neoplastic Stem Cells--cytology
Nitrophenols--pharmacology
Piperazines--pharmacology
Protein Binding
Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors
Sulfonamides--pharmacology
Survival Rate
TNF-Related Apoptosis-Inducing Ligand--metabolism
Xenograft Model Antitumor Assays