5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. [electronic resource]
Producer: 20080908Description: 4641-52 p. digitalISSN:- 1520-4804
- Alkylation
- Anti-HIV Agents -- chemical synthesis
- Benzene -- chemistry
- Chemical Phenomena
- Chemistry, Physical
- Enzyme Inhibitors -- chemical synthesis
- HIV-1 -- drug effects
- Hydrogen -- chemistry
- Models, Molecular
- Molecular Structure
- Mutation -- genetics
- Oxygen -- chemistry
- Protein Binding
- Pyrimidinones -- chemical synthesis
- RNA-Directed DNA Polymerase -- genetics
- Structure-Activity Relationship
- Sulfur Compounds -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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