5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile.
Nawrozkij, Maxim B
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. [electronic resource] - Journal of medicinal chemistry Aug 2008 - 4641-52 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm800340w doi
Alkylation
Anti-HIV Agents--chemical synthesis
Benzene--chemistry
Chemical Phenomena
Chemistry, Physical
Enzyme Inhibitors--chemical synthesis
HIV-1--drug effects
Hydrogen--chemistry
Models, Molecular
Molecular Structure
Mutation--genetics
Oxygen--chemistry
Protein Binding
Pyrimidinones--chemical synthesis
RNA-Directed DNA Polymerase--genetics
Structure-Activity Relationship
Sulfur Compounds--chemical synthesis
5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. [electronic resource] - Journal of medicinal chemistry Aug 2008 - 4641-52 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4804
10.1021/jm800340w doi
Alkylation
Anti-HIV Agents--chemical synthesis
Benzene--chemistry
Chemical Phenomena
Chemistry, Physical
Enzyme Inhibitors--chemical synthesis
HIV-1--drug effects
Hydrogen--chemistry
Models, Molecular
Molecular Structure
Mutation--genetics
Oxygen--chemistry
Protein Binding
Pyrimidinones--chemical synthesis
RNA-Directed DNA Polymerase--genetics
Structure-Activity Relationship
Sulfur Compounds--chemical synthesis