An automated, high-throughput, 384 well Cytochrome P450 cocktail IC50 assay using a rapid resolution LC-MS/MS end-point. [electronic resource]
Producer: 20081126Description: 92-9 p. digitalISSN:- 0731-7085
- Aryl Hydrocarbon Hydroxylases -- analysis
- Biological Assay
- Chromatography, Liquid -- methods
- Cytochrome P-450 CYP1A2 -- analysis
- Cytochrome P-450 CYP2B6
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP2C9
- Cytochrome P-450 CYP2D6 -- analysis
- Cytochrome P-450 CYP3A -- analysis
- Cytochrome P-450 Enzyme System -- analysis
- Dextromethorphan -- metabolism
- Diclofenac -- metabolism
- Drug Interactions
- Humans
- Hydrogen-Ion Concentration
- Inhibitory Concentration 50
- Kinetics
- Microsomes, Liver -- chemistry
- Midazolam -- metabolism
- Miniaturization
- Oxidoreductases, N-Demethylating -- metabolism
- Reference Standards
- Reproducibility of Results
- Sensitivity and Specificity
- Substrate Specificity -- drug effects
- Tacrine -- metabolism
- Tandem Mass Spectrometry -- methods
- Time Factors
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.