Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice. [electronic resource]
Producer: 20090331Description: 615-25 p. digitalISSN:- 1432-0843
- Animals
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors -- antagonists & inhibitors
- Cell Proliferation -- drug effects
- Chromatography, High Pressure Liquid
- Chromatography, Liquid
- Dimerization
- Female
- Humans
- Male
- Mice
- Mice, SCID
- Prostatic Neoplasms -- drug therapy
- Proto-Oncogene Proteins c-myc -- antagonists & inhibitors
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Thiazoles -- pharmacokinetics
- Tissue Distribution
- Treatment Outcome
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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