Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice.
Guo, Jianxia
Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice. [electronic resource] - Cancer chemotherapy and pharmacology Mar 2009 - 615-25 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1432-0843
10.1007/s00280-008-0774-y doi
Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--antagonists & inhibitors
Cell Proliferation--drug effects
Chromatography, High Pressure Liquid
Chromatography, Liquid
Dimerization
Female
Humans
Male
Mice
Mice, SCID
Prostatic Neoplasms--drug therapy
Proto-Oncogene Proteins c-myc--antagonists & inhibitors
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Thiazoles--pharmacokinetics
Tissue Distribution
Treatment Outcome
Tumor Cells, Cultured
Xenograft Model Antitumor Assays
Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice. [electronic resource] - Cancer chemotherapy and pharmacology Mar 2009 - 615-25 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1432-0843
10.1007/s00280-008-0774-y doi
Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--antagonists & inhibitors
Cell Proliferation--drug effects
Chromatography, High Pressure Liquid
Chromatography, Liquid
Dimerization
Female
Humans
Male
Mice
Mice, SCID
Prostatic Neoplasms--drug therapy
Proto-Oncogene Proteins c-myc--antagonists & inhibitors
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Thiazoles--pharmacokinetics
Tissue Distribution
Treatment Outcome
Tumor Cells, Cultured
Xenograft Model Antitumor Assays