To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions. [electronic resource]
Producer: 20080619Description: 369-80 p. digitalISSN:- 1097-4164
- Amino Acid Sequence
- Animals
- Apoptosis -- physiology
- Apoptosis Regulatory Proteins -- genetics
- BH3 Interacting Domain Death Agonist Protein -- genetics
- Bcl-2-Like Protein 11
- Cells, Cultured
- Dimerization
- Disulfides -- chemistry
- Fibroblasts -- cytology
- Humans
- Membrane Proteins -- genetics
- Mice
- Mice, Knockout
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Proto-Oncogene Proteins -- genetics
- Signal Transduction -- physiology
- bcl-2 Homologous Antagonist-Killer Protein -- chemistry
- bcl-2-Associated X Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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