Multiple molecular pathways are involved in the neuroprotection of GDNF against proteasome inhibitor induced dopamine neuron degeneration in vivo. [electronic resource]
Producer: 20080724Description: 881-90 p. digitalISSN:- 1535-3702
- Acetylcysteine -- adverse effects
- Animals
- Cysteine Proteinase Inhibitors -- adverse effects
- Disease Models, Animal
- Dopamine -- metabolism
- Glial Cell Line-Derived Neurotrophic Factor -- therapeutic use
- JNK Mitogen-Activated Protein Kinases -- metabolism
- Male
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- Nerve Degeneration -- metabolism
- Parkinson Disease -- etiology
- Phosphatidylinositol 3-Kinases -- metabolism
- Proteasome Inhibitors
- Proto-Oncogene Proteins c-akt -- metabolism
- Random Allocation
- Signal Transduction -- drug effects
- Substantia Nigra -- drug effects
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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