Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes. [electronic resource]
Producer: 20080428Description: 3277-90 p. digitalISSN:- 1529-2401
- Aged
- Aged, 80 and over
- Animals
- Animals, Newborn
- Astrocytes -- chemistry
- Brain -- pathology
- Calcium -- metabolism
- Cell Movement -- drug effects
- Cells, Cultured
- Chemokine CCL2 -- metabolism
- Chemokine CCL5 -- metabolism
- Chromatin Immunoprecipitation -- methods
- Culture Media, Conditioned -- pharmacology
- Embryo, Mammalian
- Enzyme-Linked Immunosorbent Assay -- methods
- Female
- Humans
- Huntingtin Protein
- Huntington Disease -- metabolism
- Male
- Mice
- Mice, Transgenic
- Nerve Tissue Proteins -- genetics
- Neurons -- drug effects
- Nuclear Proteins -- genetics
- Rats
- Rats, Sprague-Dawley
- Transfection -- methods
- Trinucleotide Repeat Expansion -- genetics
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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