Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.

Chou, Szu-Yi

Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Mar 2008 - 3277-90 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.0116-08.2008 doi


Aged
Aged, 80 and over
Animals
Animals, Newborn
Astrocytes--chemistry
Brain--pathology
Calcium--metabolism
Cell Movement--drug effects
Cells, Cultured
Chemokine CCL2--metabolism
Chemokine CCL5--metabolism
Chromatin Immunoprecipitation--methods
Culture Media, Conditioned--pharmacology
Embryo, Mammalian
Enzyme-Linked Immunosorbent Assay--methods
Female
Humans
Huntingtin Protein
Huntington Disease--metabolism
Male
Mice
Mice, Transgenic
Nerve Tissue Proteins--genetics
Neurons--drug effects
Nuclear Proteins--genetics
Rats
Rats, Sprague-Dawley
Transfection--methods
Trinucleotide Repeat Expansion--genetics