The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF. [electronic resource]
Producer: 20080611Description: 1525-35 p. digitalISSN:- 0950-1991
- Activins -- pharmacology
- Adaptor Proteins, Signal Transducing
- Animals
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Bone Morphogenetic Protein 4
- Bone Morphogenetic Proteins -- pharmacology
- Cell Differentiation -- drug effects
- Cells, Cultured
- Core Binding Factor Alpha 2 Subunit -- genetics
- Culture Media, Serum-Free
- DNA-Binding Proteins -- genetics
- Embryonic Stem Cells -- cytology
- Fibroblast Growth Factor 2 -- pharmacology
- Gene Expression Regulation, Developmental -- drug effects
- Hematopoiesis -- drug effects
- Hematopoietic Stem Cells -- cytology
- Homeodomain Proteins -- genetics
- LIM Domain Proteins
- Metalloproteins -- genetics
- Mice
- Proto-Oncogene Protein c-fli-1 -- genetics
- Proto-Oncogene Proteins -- genetics
- Recombinant Proteins -- pharmacology
- T-Cell Acute Lymphocytic Leukemia Protein 1
- Transcription Factors -- genetics
- Vascular Endothelial Growth Factor A -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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