The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma. [electronic resource]
Producer: 20080502Description: 295-302 p. digitalISSN:- 1365-2141
- Animals
- Antineoplastic Agents -- therapeutic use
- Apoptosis
- Aurora Kinase A
- Aurora Kinase B
- Aurora Kinases
- Cell Line, Tumor
- Flow Cytometry
- Humans
- Immunophenotyping
- Mice
- Mice, SCID
- Multiple Myeloma -- drug therapy
- Organophosphates -- therapeutic use
- Plasma Cells -- enzymology
- Protein Serine-Threonine Kinases -- analysis
- Quinazolines -- therapeutic use
- RNA, Messenger -- analysis
- Reverse Transcriptase Polymerase Chain Reaction
- Syndecan-1 -- analysis
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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