The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma.

Evans, Robert P

The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma. [electronic resource] - British journal of haematology Feb 2008 - 295-302 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1365-2141

10.1111/j.1365-2141.2007.06913.x doi


Animals
Antineoplastic Agents--therapeutic use
Apoptosis
Aurora Kinase A
Aurora Kinase B
Aurora Kinases
Cell Line, Tumor
Flow Cytometry
Humans
Immunophenotyping
Mice
Mice, SCID
Multiple Myeloma--drug therapy
Organophosphates--therapeutic use
Plasma Cells--enzymology
Protein Serine-Threonine Kinases--analysis
Quinazolines--therapeutic use
RNA, Messenger--analysis
Reverse Transcriptase Polymerase Chain Reaction
Syndecan-1--analysis
Xenograft Model Antitumor Assays