Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. [electronic resource]
Producer: 20080129Description: 969-78 p. digitalISSN:- 1089-8638
- Amino Acid Sequence
- Amino Acid Substitution
- Antibodies, Monoclonal -- chemistry
- Asparagine -- metabolism
- Computer Simulation
- Cross Reactions -- immunology
- Crystallography, X-Ray
- Glycosylation
- HIV Envelope Protein gp120 -- chemistry
- HIV-1 -- chemistry
- Humans
- Hydrogen Bonding
- Hydrophobic and Hydrophilic Interactions
- Immunoglobulin Fab Fragments -- chemistry
- Models, Chemical
- Models, Molecular
- Neutralization Tests
- Peptide Fragments -- chemistry
- Protein Conformation
- Protein Structure, Secondary
- Protein Structure, Tertiary
- Synchrotrons
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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