Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization.

Bell, Christian H

Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. [electronic resource] - Journal of molecular biology Jan 2008 - 969-78 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1089-8638

10.1016/j.jmb.2007.11.013 doi


Amino Acid Sequence
Amino Acid Substitution
Antibodies, Monoclonal--chemistry
Asparagine--metabolism
Computer Simulation
Cross Reactions--immunology
Crystallography, X-Ray
Glycosylation
HIV Envelope Protein gp120--chemistry
HIV-1--chemistry
Humans
Hydrogen Bonding
Hydrophobic and Hydrophilic Interactions
Immunoglobulin Fab Fragments--chemistry
Models, Chemical
Models, Molecular
Neutralization Tests
Peptide Fragments--chemistry
Protein Conformation
Protein Structure, Secondary
Protein Structure, Tertiary
Synchrotrons