Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine. [electronic resource]
Producer: 20081008Description: 2139-47 p. digitalISSN:- 0893-133X
- Animals
- Behavior, Animal -- drug effects
- Conditioning, Operant -- drug effects
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Excitatory Amino Acid Antagonists -- pharmacology
- Male
- Nicotine -- administration & dosage
- Nicotinic Agonists -- administration & dosage
- Photic Stimulation
- Pyridines -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Reinforcement, Psychology
- Self Administration -- methods
- Thiazoles -- pharmacology
- Tobacco Use Disorder -- psychology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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