Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine.

Palmatier, Matthew I

Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine. [electronic resource] - Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Aug 2008 - 2139-47 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

0893-133X

10.1038/sj.npp.1301623 doi


Animals
Behavior, Animal--drug effects
Conditioning, Operant--drug effects
Disease Models, Animal
Dose-Response Relationship, Drug
Excitatory Amino Acid Antagonists--pharmacology
Male
Nicotine--administration & dosage
Nicotinic Agonists--administration & dosage
Photic Stimulation
Pyridines--pharmacology
Rats
Rats, Sprague-Dawley
Reinforcement, Psychology
Self Administration--methods
Thiazoles--pharmacology
Tobacco Use Disorder--psychology